In vitro experimental evidence: Studies have shown that luteolin has significant scavenging ability for hydroxyl free radicals, DPPH free radicals, and ABTS free radicals. For example, at a concentration of 100 μg/mL, luteolin can scaveng more than 90% of DPPH free radicals and more than 92.3% of ABTS free radicals, and also shows good effects on the reduction of iron ions.
Cell experimental evidence: Luteolin can effectively prevent hydrogen peroxide-induced cell viability reduction and inhibit hydrogen peroxide-induced keratinocyte apoptosis. In addition, luteolin can also reduce oxidative stress damage to cells and improve cell survival rate.
Animal experimental evidence: In animal experiments, luteolin can significantly reduce oxidative damage markers and protect cells from oxidative stress. For example, luteolin can reduce oxidative stress damage to organs such as the heart and liver by activating the antioxidant enzyme system.